Platelet Rich Fibrin in San Juan Capistrano, CA

What Is Platelet-Rich Fibrin?

You may have heard of platelet-rich plasma (PRP) therapy as a way to promote healing after an injury or surgery or as an anti-aging treatment. Platelet-rich fibrin (PRF) works in a similar way, but with important advantages. PRF contains very high concentrations of platelets, white blood cells, fibrin, and a small number of circulating stem cells. When platelets bind to the fibrin scaffold, they become activated and release growth factors that kick-start the healing process, creating new skin cells, collagen, and blood vessels. PRF improves wound healing, collagen production, and skin elasticity, and most people are good candidates.

How Is PRF Different From PRP?

Unlike PRP, PRF does not require additives such as an anticoagulant blood thinner, making it 100 percent natural. PRF extraction provides a platelet concentration that is significantly higher than PRP. In addition, the fibrin component creates a scaffold that releases growth factors and stem cells over a longer period of time, leading to better, longer-lasting results.

How PRF Is Prepared

Like PRP, PRF is harvested from your own blood. Your provider first draws a small amount of blood from your arm, just like a routine blood draw. Instead of going to a lab, the sample is placed in a centrifuge that separates your platelets and fibrin from the other components of your blood. The PRF is then ready to use immediately in your treatment.

PRF Injections for Skin Rejuvenation

PRF can be injected on its own or combined with dermal fillers. When mixed with fillers, you enjoy the immediate volumizing effect of the filler while awaiting the long-term skin benefits of PRF. For patients with thin skin, PRF can soften hyaluronic acid filler for a smoother, more natural-looking result.

When injected without fillers, any initial volume typically dissipates within a few weeks, while the long-term effects, including skin tightening, collagen production, and enhanced skin quality, appear over three to four months. Long-term results can sometimes be seen in as little as six weeks and can last six to twelve months. Best results are achieved with a series of three to five treatments spaced six to eight weeks apart.

Dermaneedling With PRF

After a numbing cream is applied, dermaneedling (microneedling) is performed while your PRF is worked into the microscopic channels created in the skin. The PRF enhances the skin’s natural healing response and collagen production, reducing fine lines, smoothing the complexion, and potentially minimizing brown spots and acne scars.

Recovery from PRF dermaneedling typically involves a day or two of downtime, depending on the depth of treatment. Your skin will look red, similar to a sunburn, immediately afterward. You will be instructed not to wash the PRF off your face for at least eight hours, and makeup should be avoided for the first 24 hours.

What to Expect With PRF Hair Restoration

To prepare your scalp, numbing cream is applied for at least 30 minutes to minimize discomfort during the injections and dermaneedling. Treatment is minimally invasive and involves no surgery, and there is no downtime afterward. Because hair grows in cycles, a series of treatments is needed for maximum benefit, and your provider will customize a plan for you. Clinical studies have shown noticeable improvement in hair growth for men with pattern hair loss after about six months of treatment.

Combine PRF With Other Treatments

PRF enhances many other aesthetic treatments. Pair it with Morpheus8 or fractional laser resurfacing to speed healing and boost collagen, Sculptra for gradual volume, or Botox for expression lines. PRF can also support stretch mark treatment. See results in our PRF gallery, explore all cosmetic dermatology services, and learn why patients choose HK Dermatology.

Platelet-Rich Fibrin Before & After Gallery

See results from patients who received platelet-rich fibrin treatments at HK Dermatology in San Juan Capistrano, CA . Individual results vary.

Platelet-Rich Fibrin FAQs

Rejuvenate Naturally With PRF

Call HK Dermatology at (949) 248-1632 or request an appointment online to learn more about platelet-rich fibrin treatments in San Juan Capistrano, CA .